Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice
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Citreoviridin Enhances Atherogenesis in Hypercholesterolemic ApoE-Deficient Mice via Upregulating Inflammation and Endothelial Dysfunction
Vascular endothelial dysfunction and inflammatory response are early events during initiation and progression of atherosclerosis. In vitro studies have described that CIT markedly upregulates expressions of ICAM-1 and VCAM-1 of endothelial cells, which result from NF-κB activation induced by CIT. In order to determine whether it plays a role in atherogenesis in vivo, we conducted the study to i...
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ژورنال
عنوان ژورنال: Life Sciences
سال: 2012
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2012.07.010